[7] Santos Laguna 0-0 Puebla [4] 2021-05-03 00:06
Estádio: Estádio Corona Round: 17
Juiz: Erick Yair Miranda Galindo Home Manager: Guillermo Almada Away Manager: Nicolas Larcamon
Head to Head
| México - Liga MX | 2020/10/03 00:30 | Puebla v Santos Laguna | W | 0-2 |
| México - Liga MX | 2020/02/08 03:00 | Puebla v Santos Laguna | D | 2-2 |
| México - Liga MX | 2019/08/11 23:45 | Santos Laguna v Puebla | W | 4-1 |
| México - Liga MX | 2019/01/19 03:00 | Puebla v Santos Laguna | D | 1-1 |
| México - Liga MX | 2018/08/05 23:00 | Santos Laguna v Puebla | W | 2-0 |
| México - Liga MX | 2018/03/17 01:00 | Puebla v Santos Laguna | W | 0-1 |
| México - Liga MX | 2017/10/01 23:30 | Santos Laguna v Puebla | D | 0-0 |
| México - Liga MX | 2017/01/30 00:00 | Santos Laguna v Puebla | W | 2-0 |
Home History
| México - Liga MX | 2021/04/27 02:00 | Pachuca v Santos Laguna | L | 1-0 |
| México - Liga MX | 2021/04/19 00:00 | Santos Laguna v Toluca | W | 3-1 |
| México - Liga MX | 2021/04/12 00:00 | Querétaro v Santos Laguna | L | 1-0 |
| México - Liga MX | 2021/04/04 22:00 | Chivas Guadalajara v Santos Laguna | D | 1-1 |
| México - Liga MX | 2021/03/22 01:06 | Santos Laguna v Club León | L | 1-2 |
| México - Liga MX | 2021/03/14 03:05 | Tijuana v Santos Laguna | W | 0-1 |
| México - Liga MX | 2021/03/08 01:06 | Santos Laguna v Necaxa | W | 3-1 |
| México - Liga MX | 2021/03/05 03:00 | Pumas v Santos Laguna | L | 1-0 |
Away History
| México - Liga MX | 2021/04/24 00:30 | Puebla v Pumas | D | 0-0 |
| México - Liga MX | 2021/04/17 22:00 | Atlético San Luís v Puebla | W | 1-4 |
| México - Liga MX | 2021/04/13 02:00 | Pachuca v Puebla | W | 1-3 |
| México - Liga MX | 2021/04/03 01:30 | Puebla v Mazatlán FC | W | 3-1 |
| México - Liga MX | 2021/03/21 18:00 | Toluca v Puebla | D | 4-4 |
| México - Liga MX | 2021/03/13 01:30 | Puebla v Atlas | L | 0-1 |
| México - Liga MX | 2021/03/06 03:30 | Puebla v Tigres UANL | D | 1-1 |
| México - Liga MX | 2021/03/03 03:00 | Club León v Puebla | W | 1-2 |
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