Head to Head
| MLB | 2021/10/07 20:07 | CHI White Sox v HOU Astros | L | 1-6 |
| MLB | 2021/07/18 18:10 | HOU Astros v CHI White Sox | W | 0-4 |
| MLB | 2021/07/17 23:15 | HOU Astros v CHI White Sox | W | 1-10 |
| MLB | 2021/07/17 00:10 | HOU Astros v CHI White Sox | L | 7-1 |
| MLB | 2021/06/20 18:10 | CHI White Sox v HOU Astros | L | 2-8 |
| MLB | 2021/06/19 23:15 | CHI White Sox v HOU Astros | L | 3-7 |
| MLB | 2021/06/19 00:10 | CHI White Sox v HOU Astros | L | 1-2 |
| MLB | 2021/06/18 00:10 | CHI White Sox v HOU Astros | L | 2-10 |
Home History
| MLB | 2021/10/07 20:07 | CHI White Sox v HOU Astros | L | 1-6 |
| MLB | 2021/10/03 19:10 | DET Tigers v CHI White Sox | L | 5-2 |
| MLB | 2021/10/02 23:10 | DET Tigers v CHI White Sox | W | 4-5 |
| MLB | 2021/10/02 00:10 | DET Tigers v CHI White Sox | W | 1-8 |
| MLB | 2021/09/30 00:10 | CIN Reds v CHI White Sox | W | 1-6 |
| MLB | 2021/09/29 00:10 | CIN Reds v CHI White Sox | W | 1-7 |
| MLB | 2021/09/27 17:10 | CHI White Sox v DET Tigers | W | 8-7 |
| MLB | 2021/09/26 17:10 | CHI White Sox v CLE Guardians | W | 5-2 |
Away History
| MLB | 2021/10/07 20:07 | CHI White Sox v HOU Astros | W | 1-6 |
| MLB | 2021/10/03 19:10 | OAK Athletics v HOU Astros | W | 6-7 |
| MLB | 2021/10/02 23:10 | OAK Athletics v HOU Astros | W | 4-10 |
| MLB | 2021/10/02 00:10 | OAK Athletics v HOU Astros | L | 8-6 |
| MLB | 2021/09/30 23:10 | TB Rays v HOU Astros | W | 2-3 |
| MLB | 2021/09/30 00:10 | TB Rays v HOU Astros | L | 7-0 |
| MLB | 2021/09/29 00:10 | TB Rays v HOU Astros | W | 3-4 |
| MLB | 2021/09/26 20:07 | HOU Astros v OAK Athletics | L | 3-4 |
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