[4] Peñarol 0-0 Cerro Porteño [1] 2022-05-17 22:15
Estádio: Estádio Campeão do Siglo Round: 5
Juiz: Wilton Pereira Sampaio Home Manager: Jose Mauricio Larriera Away Manager: Francisco Arce
Head to Head
| Copa Libertadores | 2022/04/28 00:00 | Cerro Porteño v Peñarol | L | 1-0 |
| Mundo - Amigáveis de Clubes | 2016/01/17 01:15 | Peñarol v Cerro Porteño | W | 1-0 |
Home History
| Uruguai - Apertura | 2022/05/13 23:30 | Plaza Colonia v Peñarol | W | 0-1 |
| Uruguai - Apertura | 2022/05/08 22:00 | Peñarol v Montevideo Wanderers | W | 1-0 |
| Copa Libertadores | 2022/05/05 00:00 | Club Olimpia v Peñarol | L | 1-0 |
| Copa Libertadores | 2022/04/28 00:00 | Cerro Porteño v Peñarol | L | 1-0 |
| Uruguai - Apertura | 2022/04/23 22:00 | Torque v Peñarol | W | 0-1 |
| Uruguai - Apertura | 2022/04/16 22:00 | Cerrito v Peñarol | D | 0-0 |
| Copa Libertadores | 2022/04/13 00:30 | Peñarol v Club Olimpia | W | 2-1 |
| Uruguai - Apertura | 2022/04/09 19:00 | Peñarol v Liverpool Montevideo | W | 2-1 |
Away History
| Paraguai - División Profesional | 2022/05/14 23:15 | Club Sol de América v Cerro Porteño | L | 2-1 |
| Paraguai - División Profesional | 2022/05/12 00:15 | Cerro Porteño v Guairena FC | D | 0-0 |
| Paraguai - División Profesional | 2022/05/08 23:15 | Club Guaraní v Cerro Porteño | W | 1-2 |
| Copa Libertadores | 2022/05/04 22:00 | Colón v Cerro Porteño | L | 2-1 |
| Paraguai - División Profesional | 2022/04/30 23:45 | Cerro Porteño v Club Nacional | W | 1-0 |
| Copa Libertadores | 2022/04/28 00:00 | Cerro Porteño v Peñarol | W | 1-0 |
| Paraguai - División Profesional | 2022/04/24 21:30 | Sportivo Ameliano v Cerro Porteño | W | 0-1 |
| Paraguai - División Profesional | 2022/04/21 22:00 | Tacuary v Cerro Porteño | L | 2-0 |
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